Northampton Saints v Bristol Bears: Full team news for Sunday's game at Franklin's Gardens
Isiekwe has overcome concussion and starts at six, while Proctor is back on the wing after recovering from a calf problem.
There are six changes in all for Saints, with Proctor replacing Ollie Sleightholme and Isiekwe in for Lewis Ludlam, who is dealing with concussion.
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Hide AdRory Hutchinson returns at inside centre, with Piers Francis dropping to the bench.
Sam Matavesi, Paul Hill and Api Ratuniyarawa are all recalled, in place of Reece Marshall, Ehren Painter and Alex Moon.
Shaun Adendorff (knee), Owen Franks (foot), Danny Hobbs-Awoyemi (Achilles), Courtney Lawes (pectoral), Ludlam (concussion) and Kayde Sylvester (Achilles) are on the injured list.
Dan Biggar, Alex Mitchell and David Ribbans remain on international duty but will return to Saints next week.
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Hide AdSaints: Furbank; Proctor, Dingwall, Hutchinson, Freeman; Grayson, James; Waller (c), Matavesi, Hill; Coles, Ratuniyarawa; Isiekwe, Wood, Harrison.
Replacements: Haywood, Auterac, Painter, Moon, Tonks, Taylor, Francis, Mallinder.
Bristol Bears: Purdy; Adeolokun, O'Conor, Leiua, Naulago; Eden, Uren; Thomas, Byrne, Afoa; Joyce, Vui; Luatua (c), Thomas, Hughes.
Replacements: Capon, Woolmore, Lahiff, Holmes, Heenan, Kessell, Bedlow, Morahan.