Motorists travelling between Corby and Kettering have been warned of up to five nights of road closures.
Works on the A43 southbound near the hamburger roundabout, just to the north of Kettering, are scheduled to start on Monday (June 25).
The road will be closed from 8pm to 6am for up to five nights.
Northamptonshire County Council say they will be re-surfacing the road with anti-skid surfacing.
A council spokesman said the use of anti-skid surfacing is because that is what is on the existing surface and not because of accidents.
The diversion route uses the A6183, then Stamford Road to the A43 Corby Bypass and back down towards the hamburger roundabout.