The A43 Stamford Road in Kettering is closed both ways following a serious road traffic collision today (April 15).
The collision was between a lorry and a car and took place between the Stanion Turn off and Rushton Roundabout.
Both carriageways are currently closed at Barford Bridge as Northamptonshire Police deal with the crash.
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A spokesperson for Northamptonshire Police tweeted: "Motorists are advised to avoid the area while we deal with this incident. Thank you for your patience."
An air ambulance has landed at the scene and a woman is reported to be severely injured.
More to follow.