London Irish loss was 'a huge lesson' for Saints youngsters
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The black, green and gold were beaten 28-26 in dramatic fashion in the Premiership Rugby Cup clash at the Gtech Community Stadium.
Saints had looked to be in total control when they headed in at half-time 19-0 up.
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Hide AdBut they made three changes at the break, taking off David Ribbans, Sam Graham and Ollie Sleightholme and replacing them with Tom Lockett, Henry Pollock and Toby Thame.
Further youngsters were introduced as the second half went on, with Archie McParland becoming the youngest player in the professional era for Saints.
And the game gradually unravelled as Irish roared back from 26-7 down to snatch a late win thanks to a penalty try from the final play of the game.
Assistant coach Ferguson said: "I said to the boys that you can see how two or three knock-on effects are going to hurt you at this level.
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Hide Ad"The biggest learning from there is how we close a game out that we're in control of.
"We had six players in that group that made their professional debut and we've got the youngest Saintsman ever out there.
"These boys have gone from under-age rugby into that cauldron in a close game with a couple of minutes to go.
"This will be a huge lesson for them and that's the most important thing.
"But we don't like losing and ultimately that's what happened."