Wood, who was man of the match in the momentous 38-21 win against New Zealand at Twickenham on December 1, starts at No.6.
Two other Northampton players are in the squad, with Courtney Lawes and Dylan Hartley occupying spots on the bench.
England boss Stuart Lancaster said: “We are happy to stick with the team that did so well against New Zealand, especially in light of the fact that they have all been in good form for their clubs since then.
“There were some very tight calls, with some experienced players coming back into contention, and I am sure the bench will have a significant impact on the game.
Kettering Commonwealth Games medalist Kieran receives a hero's return
Chair role to be shared at Diamonds for this season
NCL: Brigstock stun Peterborough as Finedon pull clear
Glover’s plans for Poppies will take everything into account
Poppies boss Glover still on the hunt for fresh faces
“We can’t wait to get back to Twickenham and hopefully experience the same atmosphere as the autumn when the crowd was superb
“It means a lot to the players to have such support in the ground and watching on television.”
Ben Foden and Lee Dickson were both released by England earlier this week, and are expected to play for their club at Exeter in the LV= Cup on Saturday evening.