Proctor to miss Saints' game against Gloucester but key duo are back from injury
Proctor's place at centre is taken by Piers Francis, who starts at 12 with Rory Hutchinson moving to 13.
Francis is one of three changes to the team that lost 22-10 at the AJ Bell Stadium last weekend, with Tom Wood and Francois van Wyk also coming in.
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Hide AdWood was forced to withdraw from the Sale game due to illness, but he returns in place of Api Ratuniyarawa, with Courtney Lawes switching back to the second row.
Van Wyk comes in for Alex Waller, who drops to the bench.
David Ribbans is ready to return from a back injury and is named among the replacements, along with scrum-half Henry Taylor, who is set to make his comeback from a broken thumb.
But Saints are without Alex Mitchell (knee), Reuben Bird-Tulloch (hand), Tommy Freeman (illness), Jamie Gibson (ankle) and Ollie Sleightholme (head).
Saints: Furbank; Collins, Hutchinson, Francis, Naiyaravoro; Biggar, Reinach; van Wyk, Haywood, Painter; Moon, Lawes; Wood, Ludlam, Harrison (c).
Replacements: Matavesi, Waller, Hill, Ratuniyarawa, Ribbans, Taylor, Symons, Tuala.