The Lions duo have been named on the bench for the clash with RaboDirect PRO12 outfit Edinburgh (kick-off 7.30pm).
Saints have named a strong squad, with Tom Wood skippering the starting side and the likes of Stephen Myler and Lee Dickson also playing for the first time during pre-season.
New prop Gareth Denman, a summer recruit from Rotherham, is among the replacements following his try-scoring debut in the 45-21 win at Bedford last Friday night.
But Kahn Fotuali’i, who starred in that success, Salesi Ma’afu, Glenn Dickson and Rob Verbakel will not be involved.
Saints: Foden; K Pisi, G Pisi, Burrell, Elliott; Myler, Dickson; A Waller, Haywood, Mercey; Lawes, Day; Clark, Wood (c), van Velze.
Replacements: McMillan, Corbisiero, Denman, Craig, Nutley, Dowson, Dickinson, Glynn, Olver, Wilson, Stephenson, North, Collins, Diggin.