Wellingborough Town and S&L Corby can give their Premier Division survival chances a significant boost as they go head-to-head this weekend.
With Irchester virtually condemned to the second tier, the race is on to avoid the second relegation place.
The two mentioned protagonists, AFC Kempston and Harborough Town are separated by just six points as the campaign enters the final phase.
And both camps are well aware of the importance of Saturday’s encounter.
Jamie Wright, assistant manager at Wellingborough, said: “We know each other quite well having played a few weeks ago, it was a close game over there and it should be the same.
“Confidence is high among the lads and if we apply ourselves properly then we are confident we can win the game.”
As for S&L, boss Daren Young is seeking a positive outcome, saying: “It’s definitely a relegation batle and I won’t be happy if we only take a point.
“We could go there and shut up shop to play for a point but I don’t see why we should go and do that.”
Irchester’s fate could be sealed if they lose to leaders Holbeach and S&L are victorious.
A gap of 17 points with eight games remaining is the current state of affairs and it will take a stunning turnaround in fortunes for this to be overturned.
Also in the top flight, Desborough entertain Boston as they go in search of a first win in eight outings.
In Division One, Whitworth could do their neighbours, AFC Rushden & Diamonds, a big favour if they can get the better of league leaders Sileby Rangers.
Diamonds’ 2-2 draw with Sileby in midweek means the battle for a top two place is out of their hands and they are not back in action until Tuesday.
Elsewhere, Rushden & Higham visit Bourne, Burton Park Wanderers host Eynesbury, Raunds are at home to Olney and Thrapston face Harrowby for the second time in five days.