The main road between Northampton and Wellingbororough was closed today (Wednesday) following a collision between a van and a lorry.
Highways closed the A45 eastbound between the A428 Barnes Meadow junction to the A509 Wilby Way junction after the crash, which happened at around 6.15am.
The closure has caused miles of tailbacks for anyone travelling in that direction throughout the morning.
Police have since confirmed that a van went into the back of a flatbed lorry.
The Warwickshire and Air Ambulance landed nearby as all emergency rushed to the scene.
He was flown to University Hospital in Coventry with serious injuries.
Highways England tweeted just after 11.15am: "The A45 has reopened following a serious collision this morning. there will be traffic queues around Barnes Meadow/Riverside area but these will clear over the next 20 minutes or so."
Witnesses to the collision, or anyone with information, should contact the Northamptonshire Police Serious Collision Investigation Unit on 101 or call the Drive Watch Hotline on 0800 174615, quoting incident number 44 of 20/2/19.