A group of 10 sick and disabled pilgrims and 14 volunteer helpers set off from Corby to visit Lourdes in France.
The trip to the holy shrine is organised every year by the Kettering and Corby District Sick Pilgrims Trust.
They were joined on the journey in a jumbulance, a specially-designed coach ambulance for sick and disabled travellers, by Father Paul Inman of St Edward’s Church, Kettering.
Agnes Gallagher, chairman of the trust, said: “The takes 24 hours and we are looking forward to having a marvellous time.
“As well as visiting the shrine, we enjoy trips to many other places around Lourdes.”
The volunteers pay their own expenses and the group of helpers included nurses.
The trust raises funds during the year to pay for the pilgrimage.