Saints have decided against making wholesale changes for Friday night’s Amlin Challenge Cup semi-final clash with Harlequins at Franklin’s Gardens.
Jim Mallinder has made just four alterations to the team which beat London Irish in the Aviva Premiership on Sunday, with Ben Foden among the players given a breather.
Foden will play no part against Quins, while Courtney Lawes, Tom Wood and Luther Burrell will start on the bench.
James Wilson comes in at full-back, while there are also starts for James Craig, Calum Clark and Tom Stephenson.
Mike Haywood is back from a shoulder injury to boost a hooker department left depleted by injuries to Dylan Hartley and Matt Williams.
Meanwhile, Harlequins will be without talismanic fly-half Nick Evans, who is not in the matchday 23.
Ben Botica replaces him, while England stars Joe Marler, Chris Robshaw, Danny Care and Mike Brown are also named in the starting 15.
Saints: Wilson; Elliott, G Pisi, Stephenson, North; Myler, Fotuali’i; A Waller, McMillan, Ma’afu; Manoa, Craig; Dowson, Clark, Dickinson.
Replacements: Haywood, Denman, Mercey, Lawes, Wood, Glynn, Burrell, Collins.
Harlequins: Brown; Walker, Molenaar, Turner-Hall, Smith; Botica, Care; Marler, Ward, Sinckler; Matthews, Robson; Wallace, Robshaw, Easter.
Replacements: Buchanan, Lambert, Doran-Jones, Guest, Fa’asavalu, K Dickson, Grimoldby, Lindsay-Hague.