Stephen Myler returns from injury for Saints’ top-of-the-table Aviva Premiership showdown at Saracens on Sunday (kick-off 2pm).
Myler has missed his club’s past four games with a hamstring injury, but is back in at 10, with Lee Dickson keeping his place at scrum-half.
Saints have made a raft of changes to the team that beat Sale 28-14 in last Thursday’s Amlin Challenge Cup quarter-final, with several internationals returning.
Samu Manoa is back from USA duty, while Luther Burrell, George North, Tom Wood and Courtney Lawes also return to the starting line-up.
Saints hand a start to hooker Ross McMillan, with Mike Haywood on the bench and Dylan Hartley still sidelined with a shoulder injury.
Saracens have opted against resting a number of players following their bruising 17-15 Heineken Cup quarter-final victory at Ulster last Saturday.
Former Saints wing Chris Ashton, who scored two tries in that game, keeps his place, but back row warrior Jacques Burger is named among the replacements.
England international Alex Goode is rested after sustaining concussion in last weekend’s Ravenhill victory.
Saracens: Wyles; Ashton, Bosch, Barritt, Strettle; Farrell, de Kock; M Vunipola, Brits, Johnston; Borthwick (c), Botha; Wray, Brown, B Vunipola.
Replacements: George, Barrington, Stevens, Sheriff, Burger, Wigglesworth, Hodgson, Streather.
Saints: Foden; Elliott, G Pisi, Burrell, North; Myler, L Dickson; A Waller, McMillan, Ma’afu; Lawes, C Day; Clark, Wood (c), Manoa.
Replacements: Haywood, E Waller, Denman, Dickinson, Dowson, Fotuali’i, Hooley, Wilson.